Additional Indications

Aldehyde metabolism is potentially linked to numerous diseases and conditions. The underlying body of independently derived research suggests a wide range of potential target diseases for ALDH modulators (both activators and inhibitors), including:

  • Orphan indications
  • Cardiovascular diseases such as pulmonary artery disease and ischemic heart damage
  • Inhibition of cancer cell growth
  • Radiation dermatitis
  • Management of neurological disorders such as Parkinson's disease


Getting to the Heart of Protoemics


Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant


Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients


Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage to the Heart


ALDH2 Activator Inhibits Increased Myocardial Infarction Injury by Nitroglycerin Tolerance